The molecular study of genetic risk for periodontal disease is indicated in the following situations:
– Patients with an agressive form of periodontitis that is resistant to the applied therapy.
– Patients with periodontitis, presenting high bone degradation.
– Patients with association between periodontal disease and loss of gum tissue around the anchor holding the teeth.
– Smokers with periodontal disease symptoms.
– Relatives of patients with IL1 risk genotype.
Periodontitis is a dental disease caused by a progressive gingivitis that causes inflammation and infection of the ligaments and bones that support the teeth. Its is the leading cause of tooth loss in adults. Although it is uncommon among children, the disease increases along the adolescence.
There are factors that influence the patient’s inflammation and immune response. These are hereditary factors associated with a higher susceptibility to develop a severe symptoms of periodontitis, with the possibility of losing a tooth or an implant during the maintenance period.
The molecular study of genetic risk for quality loss of tooth enamel and tooth decay is specially indicated in the following situations:
– Changes in color of tooth enamel.
– Changes in bone mineral density.
– Darkening of tooth enamel (hypocalcifications).
– Formation of holes and grooves in tooth enamel.
– Change in thickness, calcification, mineralization, amilogenesis imperfecta of tooth enamel.
These tooth enamel alterations are due to different environmental causes (nutritional deficiencies, metabolic defects, infection, trauma, etc.) or genetic causes, the whole dental crown being affected and presenting more severe pathologies.
As a result, enamel is fragile with abnormal crystal structure, providing a rough appearance of the dental piece, colorless and prone to breakage.